Ellen Pompeo Dr. Meredith Grey Actor Patrick Dempsey Dr. Derek Shepherd Actor James Pickens Jr. Dr. Richard Webber Actor T.R. Knight Dr. George O'Malley Actor Sandra Oh Dr. Cristina Yang Actor Katherine Heigl Dr. Izzie Stevens Actor Chandra Wilson Dr. Miranda Bailey Actor Isaiah Washington Dr. Preston Burke Actor Justin Chambers Dr. Alex Karev Actor Kate Walsh Dr. Addison Montgomery Actor Jeffrey Dean Morgan Guest Star Sara Ramirez Guest Star Kate Burton Guest Star Robin Pearson Rose Guest Star Sarah Utterback Guest Star Linda Klein Guest Star Steven W. Bailey Guest Star Kathleen M. Darcy Guest Star Jeremy Rabb Guest Star Cathy Lind Hayes Guest Star Shonda Rhimes Executive Producer, Writer Mark Gordon Executive Producer Betsy Beers Executive Producer James D. Parriott Executive Producer, Writer Krista Vernoff Writer Stacy McKee Writer Mark Wilding Writer Mimi Schmir Writer Gabrielle G. Stanton Writer Zoanne Clack Writer Tony Phelan Writer Kip Koenig Writer Peter Horton Director Wendey Stanzler Director Adam Davidson Director Daniel Minahan Director Harry Werksman Writer Jeff Melman Director