Ellen Pompeo Dr. Meredith Grey Actor Patrick Dempsey Dr. Derek Shepherd Actor Sandra Oh Dr. Cristina Yang Actor Isaiah Washington Dr. Preston Burke Actor Katherine Heigl Dr. Izzie Stevens Actor Justin Chambers Dr. Alex Karev Actor T.R. Knight Dr. George O'Malley Actor Chandra Wilson Dr. Miranda Bailey Actor James Pickens Jr. Dr. Richard Webber Actor Kate Walsh Dr. Addison Montgomery Actor Sara Ramirez Dr. Callie Torres Actor Eric Dane Dr. Mark Sloan Actor Elizabeth Reaser Guest Star Kali Rocha Guest Star Dean Norris Guest Star Madison Leisle Guest Star Billy Mayo Guest Star Paul Perri Guest Star Kate Burton Guest Star Jeffrey Markle Guest Star Kelly Wolf Guest Star John Cappon Guest Star Kim Delgado Guest Star Terry Woodberry Guest Star Danielle Kennedy Guest Star Brian Chenoweth Guest Star Paul Norwood Guest Star Preston James Hillier Guest Star Yvans Jourdain Guest Star Terrance Christopher Jones Guest Star Nicole Rubio Guest Star Pete Flynn Guest Star Shonda Rhimes Executive Producer, Writer Mark Gordon Executive Producer Betsy Beers Executive Producer James D. Parriott Executive Producer Rob Corn Director