Ellen Pompeo Dr. Meredith Grey Actor Patrick Dempsey Dr. Derek Shepherd Actor Sandra Oh Dr. Cristina Yang Actor Katherine Heigl Dr. Izzie Stevens Actor Justin Chambers Dr. Alex Karev Actor T.R. Knight Dr. George O'Malley Actor Chandra Wilson Dr. Miranda Bailey Actor James Pickens Jr. Dr. Richard Webber Actor Sara Ramirez Dr. Callie Torres Actor Eric Dane Dr. Mark Sloan Actor Chyler Leigh Dr. Lexie Grey Actor Kevin McKidd Owen Hunt Actor Larry Sullivan Guest Star Emily Kuroda Guest Star Brandon Scott Guest Star Candace Brown Guest Star Michael Merton Guest Star Greta Sesheta Guest Star Mark Saul Guest Star Candice Afia Guest Star Amrapali Ambegaokar Guest Star Tymberlee Hill Guest Star Molly Kidder Guest Star Winston Story Guest Star Joseph Williamson Guest Star Martin Yu Guest Star Shonda Rhimes Executive Producer Mark Gordon Executive Producer Betsy Beers Executive Producer James D. Parriott Executive Producer Zoanne Clack Writer Jessica Yu Director