Ellen Pompeo Dr. Meredith Grey Actor Patrick Dempsey Dr. Derek Shepherd Actor Justin Chambers Dr. Alex Karev Actor Chandra Wilson Dr. Miranda Bailey Actor James Pickens Jr. Dr. Richard Webber Actor Sara Ramirez Dr. Callie Torres Actor Kevin McKidd Owen Hunt Actor Jessica Capshaw Arizona Robbins Actor Jesse Williams Jackson Avery Actor Sarah Drew April Kepner Actor Caterina Scorsone Amelia Shepherd Actor Camilla Luddington Jo Wilson Actor Jerrika Hinton Stephanie Edwards Actor Kelly McCreary Dr. Maggie Pierce Actor Debbie Allen Guest Star Jason George Guest Star Heather Matarazzo Guest Star Dan O'Brien Guest Star Giacomo Gianniotti Andrew DeLuca Guest Star Joe Adler Guest Star Irene Keng Guest Star Joe Dinicol Guest Star Nigel Gibbs Guest Star Robert Neary Guest Star Shonda Rhimes Executive Producer Mark Gordon Executive Producer Betsy Beers Executive Producer Krista Vernoff Executive Producer Rob Corn Executive Producer, Director Mark Wilding Executive Producer Allan Heinberg Executive Producer William Harper Writer