Rachel Bilson Dr. Zoe Hart Actor Jaime King Lemon Breeland Actor Wilson Bethel Wade Kinsella Actor Cress Williams Lavon Hayes Actor Scott Porter George Tucker Actor Tim Matheson Dr. Brick Breeland Actor, Director Kaitlyn Black AnnaBeth Nass Actor Maree Cheatham Bettie Breeland Guest Star Robert Buckley Peter Guest Star Josh Cooke Joel Stephens Guest Star Brandon Keener Tanner Hughes Guest Star Reginald VelJohnson Dash DeWitt Guest Star Brandi Burkhardt Crickett Guest Star Esther Scott Delma Guest Star Nicolette Robinson Tara Jane Guest Star David Moses Judge Perkins Guest Star Nicola Lambo Judy Guest Star Mallory Moye Wanda Guest Star Armelia McQueen Shula Guest Star Kati Sharp Kendra Guest Star Branton Box Randall Guest Star Nicole Pettis Mom Guest Star Leila Gerstein Executive Producer Josh Schwartz Executive Producer Stephanie Savage Executive Producer Len Goldstein Executive Producer Jason Ensler Executive Producer Jamie Gorenberg Writer