Rachel Bilson Dr. Zoe Hart Actor Jaime King Lemon Breeland Actor Wilson Bethel Wade Kinsella Actor Cress Williams Lavon Hayes Actor Scott Porter George Tucker Actor Tim Matheson Dr. Brick Breeland Actor Kaitlyn Black AnnaBeth Nass Actor Lauren Bittner Vivian Wilkes Guest Star Jon Dore Charles Guest Star Valerie Mahaffey Mae Ellen Waterloo Guest Star Anne Ramsay Winifred Wilkes Guest Star Peter Mackenzie Reverend Peter Mayfair Guest Star Steven M. Porter Frank Moth Guest Star Mallory Moye Wanda Long Guest Star Ross Philips Tom Long Guest Star Brandi Burkhardt Crickett Watts Guest Star Cole Sand Harley Wilkes II Guest Star Reginald VelJohnson Dash Guest Star John Marshall Jones Wally Guest Star John Eric Bentley Sheriff Bill Guest Star Tony Cavalero Stanley Guest Star Karla Mosley Elodie Baxter Guest Star Aynsley Bubbico Sadie Guest Star Brianne Howey Lulabelle Guest Star Mandy Levin Mrs. Mayfair Guest Star Carla Renata Susie Guest Star Susan Chuang ER Doctor Guest Star Leila Gerstein Executive Producer Josh Schwartz Executive Producer Stephanie Savage Executive Producer Len Goldstein Executive Producer Jason Ensler Executive Producer David Paymer Director Jamie Gorenberg Writer