Rachel Bilson Dr. Zoe Hart Actor Jaime King Lemon Breeland Actor Wilson Bethel Wade Kinsella Actor Cress Williams Lavon Hayes Actor Scott Porter George Tucker Actor Tim Matheson Dr. Brick Breeland Actor Kaitlyn Black AnnaBeth Nass Actor Reggie Hayes Don Todd Guest Star Maree Cheatham Bettie Breeland Guest Star Barry Watson Davis Polk Guest Star Amy Ferguson Lily Anne Lonergan Guest Star Patty McCormack Sylvie Stephens-Wilkes Guest Star Brandi Burkhardt Crickett Watts Guest Star Tony Cavalero Stanley Watts Guest Star Mallory Moye Wanda Long Guest Star Ross Philips Tom Long Guest Star Charlie Robinson Sergeant Jeffries Guest Star Steven M. Porter Frank Moth Guest Star Reginald VelJohnson Dash DeWitt Guest Star Matt Lowe Meatball Guest Star John Eric Bentley Sheriff Bill Guest Star Armelia McQueen Shula Guest Star Esther Scott Delma Warner Guest Star Kim Robillard Sal Guest Star Karla Mosley Elodie Baxter Guest Star Aynsley Bubbico Sadie Guest Star Deborah Lacey Madame Van Horn Guest Star Amaris Davidson Robin Gilmartin Guest Star Devin Hennessy Bachelor Guest Star Tisha French Don Todd's Ex Guest Star Leila Gerstein Executive Producer, Writer Josh Schwartz Executive Producer Stephanie Savage Executive Producer Len Goldstein Executive Producer Jason Ensler Executive Producer Bethany Rooney Director