Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Omar Epps Dr. Eric Foreman Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Jesse Spencer Dr. Robert Chase Actor Sela Ward Stacy Warner Guest Star Currie Graham Mark Warner Guest Star Kristoffer Polaha Jeff Forrester Guest Star Taraji P. Henson Moira Guest Star Alanna Ubach Dr. Louise Harper Guest Star Tommy Lenk Allen Guest Star Julie Quinn Matthew's Mother Guest Star Austin Whitlock Matthew Guest Star Nathan Kress Scott Guest Star Scott Kradolfer Matthew's Father Guest Star Drew Gardner Blind Guy Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer Fred Gerber Director Sara Hess Writer