Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Omar Epps Dr. Eric Foreman Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Jesse Spencer Dr. Robert Chase Actor Peter Jacobson Dr. Chris Taub Actor Olivia Wilde Thirteen, Dr. Remy Hadley Actor Lin-Manuel Miranda Juan 'Alvie' Alvarez Guest Star Zoe McLellan Sidney Merrick , Patient X Guest Star Andre Braugher Dr. Darryl Nolan Guest Star Cynthia Watros Sam Carr Guest Star David Monahan Jay Guest Star Annette M. Lesure Durdanna Guest Star Carl Gilliard Dutch Hightower Guest Star Paul Keeley Harris Guest Star Angela Martinez Nurse Jody Guest Star Ric Maddox Officer Durkee Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer David Straiton Director Doris Egan Writer David Foster Writer