Hugh Laurie Dr. Gregory House Actor Robert Sean Leonard Dr. James Wilson Actor Omar Epps Dr. Eric Foreman Actor Jesse Spencer Dr. Robert Chase Actor Peter Jacobson Dr. Chris Taub Actor Odette Annable Dr. Jessica Adams Actor Charlyne Yi Dr. Chi Park Actor Albert Owens Major Mathewson Guest Star Sharif Atkins Hayes Guest Star Arlen Escarpeta Brant Guest Star Sayeed Shahidi Evan Guest Star Kristy Johnson Joni Guest Star Alex Alexander Rita Guest Star Lindsay Zappala Gloria Guest Star Steve Nevil Mel Guest Star Adam Cagley Jason Guest Star Dava Krause Daria Guest Star Tom Riordan MP 1 Guest Star Bobbin Bergstrom Nurse Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer Julian Higgins Director Danny Weiss Writer Seth Hoffman Writer