Lucas Till Angus "Mac" MacGyver Actor George Eads Jack Dalton Actor Justin Hires Wilt Bozer Actor Tristin Mays Riley Davis Actor Meredith Eaton Matty Webber Actor Isabel Lucas Samantha Cage Actor Kate Bond Jill Guest Star Tate Donovan Oversight Guest Star William Baldwin Elwood Davis Guest Star Lance Gross Billy Colton Guest Star Reign Edwards Leanna Martin Guest Star Brad William Henke Jonah Walsh Guest Star Marco Rodríguez Luis Gomez Guest Star Bobby Hernandez Muscular Lookout Guest Star M. Serrano Grillo Guest Star Cristian Gonzales Cartel Guard 1 Guest Star Javier Vazquez Jr. Cartel Guard 3 Guest Star Stephan Jones Assassin Guest Star Paul Downs Colaizzo Executive Producer Brett Mahoney Executive Producer David Von Ancken Executive Producer Henry Winkler Executive Producer Lee David Zlotoff Executive Producer Craig S O'Neill Executive Producer, Writer David Slack Writer Stephen Herek Director