Ryan Eggold Dr. Max Goodwin Actor Freema Agyeman Dr. Helen Sharpe Actor Janet Montgomery Dr. Lauren Bloom Actor Jocko Sims Dr. Floyd Reynolds Actor Tyler Labine Dr. Iggy Frome Actor Anupam Kher Dr. Vijay Kapoor Actor Ana Villafañe Dr. Valentina Castro Guest Star Margot Bingham Evie Garrison Guest Star JJ Feild Dr. Zach Ligon Guest Star Shamika Cotton Martha Randle Guest Star Matthew DeTitta C.O. Lopez Guest Star Alejandro Hernández ED Nurse Casey Acosta Guest Star Lissa Danshaw Paramedic Guest Star Maria Elena Ramirez Dr. Rae Proctor Guest Star Debra Monk Chairwoman Karen Brantley Guest Star Jennifer Betit Yen Nurse Aimee Kamoe Guest Star Olivia Khoshatefeh ED Resident Yasmin Turan Guest Star Alexander Jones Burly C.O. Guest Star Murphy Guyer Warden Hughes Guest Star David E. Chen C.O. Green Guest Star Shawna Hamic Charly Yarborough Guest Star Matthew Jeffers ED Resident Mark Walsh Guest Star Ivory Aquino Fran Meale Guest Star Selena Nelson C.O. Harris Guest Star Nikiya Mathis Pearl Guest Star Susanna Guzman C.O. Sanchez Guest Star Ashlie Atkinson Jackie Connor Guest Star Lisa Ferreira Suzan Parker Guest Star Idalia Limón Adrienne Guest Star Marinda Anderson Dr. Valarie Jessup Guest Star Tim Simon Lab Tech Tony George Guest Star Drae Campbell Dezi Nelson Guest Star Dina Pearlman C.O. Roberts Guest Star Cori Dioquino Nurse Eddie Guest Star Jace Bently Darrrell Randle Guest Star Patrick Cann Corrections Officer Guest Star Michiko Sasaki Rikers Physician Guest Star Dierdre Friel Ella Guest Star Lisa O'Hare Georgia Goodwin Guest Star April L. Hernandez Dominique Ann Reed Guest Star Heather Girardi Guard Leonard Guest Star Dwelvan David Guard Mashburn Guest Star David Schulner Executive Producer Peter Horton Executive Producer Kate Dennis Executive Producer Eric Manheimer Executive Producer Michael Slovis Director Graham Norris Writer