Ryan Eggold Dr. Max Goodwin Actor Freema Agyeman Dr. Helen Sharpe Actor Janet Montgomery Dr. Lauren Bloom Actor Jocko Sims Dr. Floyd Reynolds Actor Tyler Labine Dr. Iggy Frome Actor Nora Clow Luna Guest Star Opal Clow Luna Guest Star Jack Doolan Colin Guest Star Shiva Kalaiselvan Dr. Leyla Shinwari Guest Star Matthew Jeffers ED Chief Resident Dr. Mark Walsh Guest Star Garrett Young Adam Wilder Guest Star Sandra Mae Frank Dr. Elizabeth Wilder Guest Star Isaiah Seward Paramedic Durango Guest Star Michael Castillejos Dion Jimenez Guest Star Becca Ballenger Paramedic Goodrich Guest Star Keren Lugo Dr. Diana Flores Guest Star Richard Crawford Cabbie Malcolm Goode Guest Star Jenny Jules Serwa Sharpe Guest Star Phoebe Dunn Waiter Guest Star Jowin Marie Batoon Trauma Nurse Guest Star Olivia Khoshatefeh ED Resident Yasmin Turan Guest Star Ehad Berisha ED Resident Huxley Guest Star Amaia Arana ED Resident Roxana Zamaya Guest Star Atibon Nazaire Janitor Carl Guest Star Dierdre Friel Ella Guest Star Griffin Osborne Ian Guest Star Luke Antony Neville Duncan Guest Star Ryan Faucette Trevor Vaughan Guest Star Conner Max Ben Meyer Guest Star Nicole Villamil Delia Jimenez Guest Star David Schulner Executive Producer Peter Horton Executive Producer Michael Slovis Executive Producer David Foster Executive Producer, Writer Aaron Ginsburg Executive Producer Shaun Cassidy Executive Producer Olenka Denysenko Director