Dylan Walsh Dr. Sean McNamara Actor Julian McMahon Dr. Christian Troy Actor John Hensley Matt McNamara Actor Joely Richardson Julia McNamara Actor Valerie Cruz Grace Santiago Actor Jonathan Del Arco Sofia Lopez Guest Star Nancy Cassaro Suzanne Epstein Guest Star Jessalyn Gilsig Gina Russo Guest Star Robert LaSardo Escobar Gallardo Guest Star Marisol Nichols Antonia Ramos Guest Star Daniel Zacapa Pepe Guest Star Kelsey Batelaan Annie McNamara Guest Star Paul Cassell Brad Guest Star Angelica Castro María Amador Guest Star Susan Chuang Pilates Instructor Guest Star Roma Maffia Dr. Liz Cruz Guest Star Linda Klein Nurse Linda Guest Star