Seth MacFarlane Captain Ed Mercer Actor, Executive Producer Adrianne Palicki Commander Kelly Grayson Actor Penny Johnson Dr. Claire Finn Actor Scott Grimes Lieutenant Gordon Malloy Actor Peter Macon Lieutenant Commander Bortus Actor Halston Sage Chief Security Officer Alara Kitan Actor J. Lee Lieutenant John Lamarr Actor Mark Jackson Isaac Actor Chad L. Coleman Klyden Actor Norm Macdonald Yaphit Guest Star Robert Knepper Hamelac Guest Star James Morrison Kemka Guest Star Max Burholder Tomilin Guest Star Brannon Braga Executive Producer David A. Goodman Executive Producer Jason Clark Executive Producer Liz Heldens Executive Producer