Dominic West Det. James "Jimmy" McNulty Actor John Doman William A. Rawls Actor Frankie Faison Comm. Ervin H. Burrell Actor Wood Harris Avon Barksdale Actor Domenick Lombardozzi Det. Thomas "Herc" Hauk Actor Deirdre Lovejoy Rhonda Pearlman Actor Wendell Pierce Det. William "Bunk" Moreland Actor Lance Reddick Lt. Cedric Daniels Actor Andre Royo Bubbles Actor Sonja Sohn Det. Shakima "Kima" Greggs Actor J.D. Williams Preston "Bodie" Broadus Actor Seth Gilliam Sgt. Ellis Carver Actor Clarke Peters Det. Lester Freamon Actor Jim True-Frost Det. Roland "Prezbo" Pryzbylewski Actor Michael Kenneth Williams Omar Little Actor Corey Parker Robinson Det. Leander Sydnor Actor Robert Wisdom Howard "Bunny" Colvin Actor Aidan Gillen Thomas "Tommy" Carcetti Actor Jamie Hector Marlo Stanfield Actor Chad L. Coleman Dennis "Cutty" Wise Actor Isiah Whitlock Jr. State Sen. R. Clayton "Clay" Davis Actor Glynn Turman Mayor Clarence V. Royce Actor Reg E. Cathey Norman Wilson Guest Star Jermaine Crawford Duquan "Dukie" Weems Guest Star Maestro Harrell Randy Wagstaff Guest Star Julito McCullum Namond Brice Guest Star Mack Wilds Michael Lee Guest Star Gbenga Akinnagbe Chris Partlow Guest Star Robert F. Chew Joseph "Proposition Joe" Stewart Guest Star Anwan Glover Slim Charles Guest Star Method Man Melvin "Cheese" Wagstaff Guest Star Al Brown Col. Stanislaus Valchek Guest Star Jay Landsman Lt. Dennis Mello Guest Star Delaney Williams Sgt. Jay Landsman Guest Star Ramón Rodríguez Renaldo Guest Star Thuliso Dingwall Kenard Guest Star Stacie Davis Ms. Duquette Guest Star Dan DeLuca David Parenti Guest Star Susan Duvall Assistant Principal Marcia Donnelly Guest Star Sandi McCree De'Londa Brice Guest Star Felicia Pearson Felicia "Snoop" Pearson Guest Star Franklin Ojeda Smith Minister Guest Star Felix Stevenson Reverend Frank Reid Guest Star Edward Norris Det. Edward Norris Guest Star Michael Salconi Off. Michael "Sanny" Santangelo Guest Star Gregory L. Williams Det. Michael Crutchfield Guest Star Brian Anthony Wilson Det. Vernon Holley Guest Star Mark Joy Ed Bowers Guest Star Michael Willis Andy Krawczyk Guest Star Nathan Corbett Donut Guest Star Brad Anderson Director David Simon Writer Ed Burns Writer