Dominic West Det. James "Jimmy" McNulty Actor John Doman William A. Rawls Actor Frankie Faison Comm. Ervin H. Burrell Actor Wood Harris Avon Barksdale Actor Domenick Lombardozzi Det. Thomas "Herc" Hauk Actor Deirdre Lovejoy Rhonda Pearlman Actor Wendell Pierce Det. William "Bunk" Moreland Actor Lance Reddick Lt. Cedric Daniels Actor Andre Royo Bubbles Actor Sonja Sohn Det. Shakima "Kima" Greggs Actor J.D. Williams Preston "Bodie" Broadus Actor Seth Gilliam Sgt. Ellis Carver Actor Clarke Peters Det. Lester Freamon Actor Jim True-Frost Det. Roland "Prezbo" Pryzbylewski Actor Michael Kenneth Williams Omar Little Actor Corey Parker Robinson Det. Leander Sydnor Actor Robert Wisdom Howard "Bunny" Colvin Actor Aidan Gillen Thomas "Tommy" Carcetti Actor Jamie Hector Marlo Stanfield Actor Chad L. Coleman Dennis "Cutty" Wise Actor Isiah Whitlock Jr. State Sen. R. Clayton "Clay" Davis Actor Glynn Turman Mayor Clarence V. Royce Actor Reg E. Cathey Norman Wilson Guest Star Jermaine Crawford Duquan "Dukie" Weems Guest Star Maestro Harrell Randy Wagstaff Guest Star Julito McCullum Namond Brice Guest Star Mack Wilds Michael Lee Guest Star Gbenga Akinnagbe Chris Partlow Guest Star Neal Huff Chief of Staff Michael Steintorf Guest Star Robert F. Chew Joseph "Proposition Joe" Stewart Guest Star Anwan Glover Slim Charles Guest Star Method Man Melvin "Cheese" Wagstaff Guest Star Benjamin Busch Off. Anthony Colicchio Guest Star Boris McGiver Lt. Charles Marimow Guest Star Delaney Williams Sgt. Jay Landsman Guest Star Marlyne Barrett Council President Nerese Campbell Guest Star S. Robert Morgan Butchie Guest Star Ramón Rodríguez Renaldo Guest Star Shamika Cotton Raylene Lee Guest Star Stacie Davis Ms. Duquette Guest Star Susan Duvall Assistant Principal Marcia Donnelly Guest Star Rick Otto Off. Kenneth Dozerman Guest Star Frederick Strother State Delegate Odell Watkins Guest Star Melvin Williams Deacon Guest Star Nathan Corbett Donut Guest Star Thuliso Dingwall Kenard Guest Star Sandi McCree De'Londa Brice Guest Star Felicia Pearson Felicia "Snoop" Pearson Guest Star Jeffrey Lorenzo Karim Williams Guest Star Gene Terinoni Lt. Jimmy Asher Guest Star Kelli R. Brown Kimmy Guest Star Dan DeLuca David Parenti Guest Star Yolanda Gaskins School Board Representative Guest Star Michael Willis Andy Krawczyk Guest Star Joe Chappelle Director Ed Burns Writer George Pelecanos Writer