James Spader Raymond "Red" Reddington Actor Megan Boone Elizabeth Keen Actor Diego Klattenhoff Donald Ressler Actor Harry Lennix Harold Cooper Actor Ryan Eggold Tom Keen Actor Mozhan Marnò Samar Navabi Actor Amir Arison Aram Mojtabai Actor Mary-Louise Parker Naomi Hyland Guest Star Paul Reubens Mr. Vargas Guest Star Lee Tergesen Frank Hyland Guest Star Hal Ozsan Ezra Guest Star Jon Bokenkamp Executive Producer John Eisendrath Executive Producer John Davis Executive Producer John Fox Executive Producer