America Ferrera Betty Suarez Actor Eric Mabius Daniel Meade Actor Alan Dale Bradford Meade Actor Tony Plana Ignacio Suarez Actor Ana Ortiz Hilda Suarez Actor Judith Light Claire Meade Actor Christopher Gorham Henry Grubstick Actor Ashley Jensen Christina McKinney Actor Becki Newton Amanda Tanen, Fey Sommers Actor Michael Urie Marc St. James Actor Mark Indelicato Justin Suarez Actor Rebecca Romijn Alexis Meade Actor Vanessa Williams Wilhelmina Slater Actor James Van Der Beek Luke Carnes Guest Star John Cho Kenny Guest Star Illeana Douglas Sheila Guest Star Robert Desiderio Mr. Gallico Guest Star Rebecca Wisocky Marsha Stein Guest Star Victor Garber Professor Barrett Guest Star Dylan Kenin Amped Up Guy Guest Star Robyn Moran Cucina Editor Guest Star Jonathan Kehoe Player Guest Star Ashley Rickards Sharra Guest Star Jeff Staron Emo Guy Guest Star Colin Kim Jeremy Guest Star Ginny Weirick Leather Girl Guest Star Mathias Alvarez Phillip Guest Star Michael Ark Studio 54 Magnum Guest Star Guile Branco Bartender Guest Star Clifford Parks Writing Class Nerd Guest Star Silvio Horta Executive Producer Ben Silverman Executive Producer Salma Hayek Executive Producer Jose Tamez Executive Producer Tucker Gates Director Sarah Kucserka Writer Veronica Becker Writer