America Ferrera Betty Suarez Actor Eric Mabius Daniel Meade Actor Alan Dale Bradford Meade Actor Tony Plana Ignacio Suarez Actor Ana Ortiz Hilda Suarez Actor Judith Light Claire Meade Actor Christopher Gorham Henry Grubstick Actor Ashley Jensen Christina McKinney Actor Becki Newton Amanda Tanen Actor Michael Urie Marc St. James Actor Mark Indelicato Justin Suarez Actor Rebecca Romijn Alexis Meade Actor Vanessa Williams Wilhelmina Slater Actor David Blue Cliff St. Paul Actor John Cho Kenny Guest Star Lorraine Toussaint Yoga Guest Star Larry Dorf Steve Guest Star Lillian Adams Esther Guest Star Hilda DeVoine Lucille Guest Star Bunny Levine Mabel Guest Star Dustin Moss Gus Guest Star Ashley Rickards Sharra Guest Star Chancellor Miller Derek Guest Star Artemis Pebdani Rita Guest Star Jodi Carlisle Customer Guest Star Peter Waldman Violinist Guest Star Sheila R. Lawrence Rose Seller Guest Star, Writer Rafael Amaya Lorenzo -- telenovela segment Guest Star Josh Diaz Bowling Alley Dancer Guest Star Jacqueline García Rosa -- telenovela segment Guest Star Galilea Montijo Selena -- telenovela segment Guest Star David Ostrosky Señor Delgado -- telenovela segment Guest Star José Luis Reséndez Esteban -- telenovela segment Guest Star Silvio Horta Executive Producer Ben Silverman Executive Producer Salma Hayek Executive Producer Jose Tamez Executive Producer Wendey Stanzler Director