Jennifer Chambers Lynch Director, Screenwriter Julian Sands Dr. Nick Cavanaugh Actor Sherilyn Fenn Helena Actor Bill Paxton Ray O'Malley Actor Kurtwood Smith Dr. Alan Harrison Actor Betsy Clark Anne Garrett Actor Nicolette Scorsese Fantasy Lover , Nurse Actor Kim Lentz Nurse Diane Actor Meg Register Marion Cavanaugh Actor Carl Mazzocone Producer Philippe Caland Producer Larry Sugar Executive Producer James R. Schaeffer Executive Producer Bojan Bazelli Cinematographer Frank Byers Cinematographer David Finfer Film Editing Graeme Revell Original Music Paul Huggins Production Design, Art Director Sharon Braunstein Set Decoration Ferne Cassel Casting