Dennis Hopper Billy Director, Actor Peter Fonda Wyatt Actor, Producer Jack Nicholson George Hanson Actor Antonio Mendoza Jesus Actor Phil Spector Connection Actor Mac Mashourian Bodyguard Actor Warren Finnerty Rancher Actor Tita Colorado Rancher's Wife Actor Luke Askew Stranger on highway Actor Luana Anders Lisa Actor Sabrina Scharf Sarah Actor Sandy Brown Wyeth Joanne Actor Robert Walker Jr. Jack Actor George Fowler Jr. Guard Actor Toni Basil Mary Actor Karen Black Karen Actor Keith Green Sheriff Actor Terry Southern Writer Bob Rafelson Producer Bert Schneider Executive Producer László Kovács Cinematographer Donn Cambern Film Editing Roger McGuinn Original Music Jeremy Kay Art Director