Janicza Bravo Director, Screenwriter, Executive Producer Brett Gelman Isaac Actor, Screenwriter, Executive Producer Judy Greer Ramona Actor Michael Cera Alex Actor Nia Long Cleo Actor Shiri Appleby Ruthie Actor David Paymer Dr. Gold Actor Fred Melamed Howard Actor Jon Daly Toby Actor Rhea Perlman Esther Actor Gillian Jacobs Tracy Actor Martin Starr Adam Actor Marla Gibbs Lily Actor David Bernon Producer Paul Bernon Producer Houston King Producer Sam Slater Producer David Hinojosa Executive Producer Christine Vachon Executive Producer Jason McCormick Cinematographer Joi McMillon Film Editing Grace Alie Production Design Ali Rubinfeld Art Director Ariel Goodman-Weston Costume Design Emily Schweber Casting