Ray Patterson Director Mel Blanc Barney Rubble , Dino , Mr. Spacely Voice Daws Butler Elroy Jetson , Cogswell , Henry Orbit Voice Hamilton Camp Turk Tarpit Voice Henry Corden Fred Flintstone , Knight Voice Don Messick Astro , R.U.D.I , Mac , Announcer , Store Manager , Robot Voice George O'Hanlon George Jetson Voice Penny Singleton Jane Jetson Voice John Stephenson Mr. Slate , Moderator , Investor , Poker Player Voice Jean Vander Pyl Wilma Flintstone , Rosie , Mrs. Spacely Voice Janet Waldo Judy Jetson , Female Computer Voice Frank Welker Dan Rathmoon , Johnny , Mr. Goldbrick Voice