Critic Consensus: A.P. Bio has some genuine laughs, but audiences have already seen plenty of authority figures behaving badly -- and have a right to expect more from this promising premise and talented cast.
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Seeing [Glenn] Howerton in the more conventionally structured "A.P. Bio" is a pleasure, just as it's a treat to see Kaitlin Olson, another "Philadelphia" cast member, on her Fox sitcom, "The Mick."
Howerton makes the most of his central ribald rogue role while Oswalt seemingly was built to be a bumbler.
A.P. Bio is an innately watchable sitcom, but ... O'Brien has an eye toward longevity as he builds intriguing details into Jack's life, meant for later exploration, and utilizes a strong supporting cast who play people with their own bits of bad in them.
In spite of impressive pedigree and cast, along with a few laughs, A.P. Bio ultimately earns a gentlemanly C.
Ultimately this is a star vehicle for Howerton, with a sidecar for Oswalt.
A.P. Bio feels less like a straight A-student and more like the interesting slacker in the back of the room cruising on Bs and Cs. It's a good look for NBC right now, but also for Howerton, who couldn't be more addicting on screen.
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