Annie Potts Mary Elizabeth "M.E." O'Brien Sims Actor Lorraine Toussaint Rene Jackson Actor Mae Middleton Mary Elizabeth Actor Shari Dyon Perry Rene Actor Chris Mulkey Colliar Sims Actor Dan Byrd Young Colliar Actor Christopher Winsor Davis Sims Actor Olivia Friedman Kelly Sims Williams Actor Donzaleigh Abernathy Sara Jackson Actor William Converse-Roberts Actor Nancy McLoughlin Actor Millie Perkins Guest Star Mary-Pat Green Guest Star Tangie Ambrose Guest Star