Gary Sinise Det. Mack "Mac" Taylor Actor Melina Kanakaredes Det. Stella Bonasera Actor Carmine Giovinazzo Det. Danny Messer Actor Hill Harper Dr. Sheldon Hawkes Actor Vanessa Ferlito Aiden Burn Actor Eddie Cahill Det. Donald Flack, Jr. Actor Penelope Ann Miller Rose Whitley Guest Star Raphael Sbarge District Attorney Latham Guest Star Garret Dillahunt Steve Collins Guest Star Emily Harrison Amy Madoff Guest Star Dave Power James Madoff Guest Star Sandy Martin Mrs. Collins Guest Star Wil Horneff Dennis Sporco Guest Star Ben Bode Professor Newlin Guest Star Jesse Colliver Paramedic Guest Star Pinky Villasenor ND Tech Guest Star Tim Sitarz Adam Baxter Guest Star Danny Wynands Clark Boyd Guest Star Jerry Bruckheimer Executive Producer Carol Mendelsohn Executive Producer Ann Donahue Executive Producer Anthony Zuiker Executive Producer Danny Cannon Executive Producer Andrew Lipsitz Executive Producer, Writer Duane Clark Director