Gary Sinise Det. Mack "Mac" Taylor Actor Melina Kanakaredes Det. Stella Bonasera Actor Carmine Giovinazzo Det. Danny Messer Actor Hill Harper Dr. Sheldon Hawkes Actor Eddie Cahill Det. Donald Flack, Jr. Actor Anna Belknap Det. Lindsay Monroe Messer Actor A.J. Buckley Adam Ross Actor Emmanuelle Vaugier Detective Jessica Angell Guest Star Robert Joy Dr. Sid Hammerback Actor Craig T. Nelson Robert Dunbrook Guest Star Julia Ormond Deputy Inspector Gillian Whitford Guest Star Thad Luckinbill Connor Dunbrook Guest Star Tony Amendola Professor Papakota Guest Star Casey LaBow Ella McBride Guest Star Adoni Maropis Large Man , Diakos Guest Star Ethan Erickson Brendon Walsh Guest Star Nelly Terrence Davis Guest Star Paul Papadakis George Kolovos Guest Star Kathleen Munroe Samantha Flack Guest Star Brian Oblak FBI Agent Walsh Guest Star Jerry Bruckheimer Executive Producer Carol Mendelsohn Executive Producer Ann Donahue Executive Producer Anthony Zuiker Executive Producer Danny Cannon Executive Producer Andrew Lipsitz Executive Producer Pam Veasey Writer Wendy Battles Writer Trey Callaway Writer Zachary Reiter Writer John Dove Writer Sam Humphrey Writer Barbie Kligman Writer Daniele Nathanson Writer Bill Haynes Writer Rob Bailey Director Peter M. Lenkov Writer Alex Zakrzewski Director Oz Scott Director Matt Earl Beesley Director