Gary Sinise Det. Mack "Mac" Taylor Actor Sela Ward Jo Danville Actor Carmine Giovinazzo Det. Danny Messer Actor Hill Harper Dr. Sheldon Hawkes Actor Eddie Cahill Det. Donald Flack, Jr. Actor Anna Belknap Det. Lindsay Monroe Messer Actor A.J. Buckley Adam Ross Actor Robert Joy Dr. Sid Hammerback Actor Michael McMillian Neal Cooper Guest Star Marla Sokoloff Abigail West Guest Star Carter MacIntyre Chris Boyle Guest Star Deja Howell Guest Star Alexa Havins Jessica Thompson Guest Star Toni Wynne Guest Star Leo J Clark Guest Star Shannon Wada Guest Star Paul Ben-Victor Carmen Enzo Guest Star Haviland Stillwell Guest Star Brian Collins John Everett Guest Star Carl Ciarfalio Carlo Guest Star Henry Kingi Jr. Guest Star Jerry Bruckheimer Executive Producer Carol Mendelsohn Executive Producer Ann Donahue Executive Producer Anthony Zuiker Executive Producer Danny Cannon Executive Producer Andrew Lipsitz Executive Producer Adam Targum Writer Skip Sudduth Director