Gary Sinise Det. Mack "Mac" Taylor Actor Sela Ward Jo Danville Actor Carmine Giovinazzo Det. Danny Messer Actor Hill Harper Dr. Sheldon Hawkes Actor Eddie Cahill Det. Donald Flack, Jr. Actor Anna Belknap Det. Lindsay Monroe Messer Actor A.J. Buckley Adam Ross Actor Robert Joy Dr. Sid Hammerback Actor Natalie Martinez Detective Jamie Lovato Guest Star Johann Urb Grant Holliston Guest Star Laura Vandervoort Macy Sullivan Guest Star Robert Baker Calvin George Guest Star Andy T. Tran Thug Guest Star Moneer Yaqubi Alex Henley Guest Star Daniel Theodore Gabe Breslin Guest Star Jerry Bruckheimer Executive Producer Carol Mendelsohn Executive Producer Ann Donahue Executive Producer Anthony Zuiker Executive Producer Danny Cannon Executive Producer Andrew Lipsitz Executive Producer David Fallon Writer Pam Veasey Writer, Director