Teri Hatcher Susan Mayer Actor Felicity Huffman Lynette Scavo Actor Marcia Cross Bree Hodge Actor Eva Longoria Gabrielle Solis Actor Nicollette Sheridan Edie Britt Actor Alfre Woodard Betty Applewhite Actor Brenda Strong Mary Alice Young Actor James Denton Mike Delfino Actor Doug Savant Tom Scavo Actor Ricardo Antonio Chavira Carlos Solis Actor Mark Moses Paul Young Actor Richard Burgi Karl Mayer Actor Roger Bart George Williams Actor Cody Kasch Zach Young Actor Andrea Bowen Julie Mayer Actor Shawn Pyfrom Andrew Van De Kamp Actor Joy Lauren Danille Van De Kamp Actor Mehcad Brooks Matthew Applewhite Actor Jesse Metcalfe John Rowland Actor Zane Huett Parker Scavo Actor Lesley Ann Warren Sophie Bremmer Guest Star Bob Newhart Morty Flickman Guest Star Danny Trejo Hector Ramos Guest Star Kathryn Joosten Mrs. McCluskey Guest Star Mia Wesley Leila Mitzman Guest Star John Bradley Ty Grant Guest Star Pat Crawford Brown Ida Greenberg Guest Star Charlie Babcock Stu Durber Guest Star Charles Pratt Jr. Executive Producer Marc Cherry Executive Producer Tom Spezialy Executive Producer Michael Edelstein Executive Producer Jenna Bans Writer Stephen Cragg Director