Teri Hatcher Susan Mayer Actor Felicity Huffman Lynette Scavo Actor Marcia Cross Bree Hodge Actor Eva Longoria Gabrielle Solis Actor Nicollette Sheridan Edie Britt Actor Alfre Woodard Betty Applewhite Actor Brenda Strong Mary Alice Young Actor James Denton Mike Delfino Actor Doug Savant Tom Scavo Actor Ricardo Antonio Chavira Carlos Solis Actor Mark Moses Paul Young Actor Richard Burgi Karl Mayer Actor Roger Bart George Williams Actor Cody Kasch Zach Young Actor Andrea Bowen Julie Mayer Actor Shawn Pyfrom Andrew Van De Kamp Actor Joy Lauren Danille Van De Kamp Actor Mehcad Brooks Matthew Applewhite Actor Jesse Metcalfe John Rowland Actor Zane Huett Parker Scavo Actor Jay Harrington Dr. Ron McCready Guest Star Currie Graham Ed Ferrara Guest Star Jeff Doucette Father Crowley Guest Star Carol Mansell Pat Ziegler Guest Star Gwendoline Yeo Xiao-Mei Guest Star Bob Gunton Noah Taylor Guest Star Nick Chinlund Detective Sullivan Guest Star Harriet Sansom Harris Felicia Tilman Guest Star Elizabeth Sung Translator Guest Star Carlos Jacott Gary Grantham Guest Star Michael McDonald Steven Guest Star Joe Ochman Justice of the Peace Guest Star Jane Lynch Maxine Bennett Guest Star Andre Ware FBI Agent #1 Guest Star Jill Brennan Tish Atherton Guest Star Jim Cantafio FBI Agent #2 Guest Star Dagney Kerr Nurse Ruth Ann Heisel Guest Star Tim Monsion Dr. Cunningham Guest Star Charles Pratt Jr. Executive Producer Marc Cherry Executive Producer Tom Spezialy Executive Producer, Writer Michael Edelstein Executive Producer Robert Duncan McNeill Director