Jane Seymour Dr. Michaela "Mike" Quinn Actor Joe Lando Byron Sully Actor Chad Allen Matthew Cooper Actor Shawn Toovey Brian Cooper Actor Jessica Bowman Colleen Cooper Actor Orson Bean Loren Bray Actor Barbara Babcock Dorothy Jennings Actor Jim Knobeloch Jake Slicker Actor Geoffrey Lower Rev. Timothy Johnson Actor Megan Calabrese Guest Star William Shockley Hank Claggerty Actor Henry G. Sanders Robert E. Actor Jonelle Allen Grace Actor Ash Adams Preston A. Lodge III Actor Brandon Douglas Dr. Andrew Cook Actor Alexandria McKenzie Calabrese Actor Larry Sellers Cloud Dancing Actor John Schneider Daniel Simon Actor Frank Collison Horace Bing Actor Alex Meneses Teresa Morales Actor Beth Sullivan Executive Producer Carl Binder Executive Producer, Writer Bethany Rooney Director Terrence O'Hara Director James Keach Director Gwen Arner Director Philip Gerson Writer Steven Dubin Director Steve Dubin Director Jerry London Director Chris Abbott Writer Eric Tuchman Writer Charles Abbott Writer Rick Najera Writer Joel Ziskin Writer Mike Lyons Writer Jeanne Davis Writer Julie Henderson Writer Kim Wells Writer