Jane Seymour Dr. Michaela "Mike" Quinn Actor Joe Lando Byron Sully Actor Chad Allen Matthew Cooper Actor Shawn Toovey Brian Cooper Actor Jessica Bowman Colleen Cooper Actor Orson Bean Loren Bray Actor Jim Knobeloch Jake Slicker Actor Geoffrey Lower Rev. Timothy Johnson Actor William Shockley Hank Claggerty Actor Henry G. Sanders Robert E. Actor Jonelle Allen Grace Actor Ash Adams Preston A. Lodge III Actor Brandon Douglas Dr. Andrew Cook Actor Barbara Babcock Dorothy Jennings Actor Frank Collison Horace Bing Actor Larry Sellers Cloud Dancing Actor John Schneider Daniel Simon Actor Alexandria McKenzie Calabrese Actor Alex Meneses Teresa Morales Actor Georgann Johnson Guest Star Alley Mills Guest Star Haylie Johnson Guest Star Janna Michaels Guest Star Alicia Hoge Guest Star Lisa Barnes Guest Star Jerry Giles Guest Star Elinor Donahue Guest Star Beth Sullivan Executive Producer Carl Binder Executive Producer