Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Joan Watson Actor Aidan Quinn Captain Thomas Gregson Actor Jon Michael Hill Detective Marcus Bell Actor Jeremy Cohenour Brandon Falchek Guest Star Julien Seredowych Galen Barrow Guest Star Anastasia Griffith Agatha Spurrell Guest Star Devin Ratray Gordon Meadows Guest Star Kate Jennings Grant Lydia Guerrero Guest Star Andre Ward Bobby Alacqua Guest Star Bill English Eric Frazier Guest Star Zoe Winters Mahra Kemp Guest Star Marc Damon Johnson Dispatcher Guest Star Eshan Bay Roommate Guest Star Robert Doherty Executive Producer Carl Beverly Executive Producer Sarah Timberman Executive Producer Craig Sweeny Executive Producer Jordan Rosenberg Writer Bob Goodman Writer Seith Mann Director