Jonny Lee Miller Sherlock Holmes Actor Lucy Liu Joan Watson Actor Aidan Quinn Captain Thomas Gregson Actor Jon Michael Hill Detective Marcus Bell Actor James Frain Odin Reichenbach Actor Joseph Lyle Taylor Detective Owen Calabrissi Guest Star Marjan Neshat Detective Farrad Guest Star Christa Scott-Reed Meredith Sagehorn Guest Star Charles Borland Judd Foley Guest Star Matthew Boston Mack Leehoven Guest Star William Hill Jim Bendix Guest Star Tramell Tillman Detective Ocasio Guest Star Michael Satow Dalton Weller Guest Star James Murtaugh Lawyer Guest Star Ally Ioannides Cassie Lenue Guest Star Kelsey Rainwater Social Worker Guest Star Robert Doherty Executive Producer Carl Beverly Executive Producer Sarah Timberman Executive Producer John Polson Executive Producer Jason Tracey Executive Producer Bob Goodman Writer Michael Smith Director