Anthony Edwards Dr. Mark Greene Actor George Clooney Dr. Doug Ross Actor Sherry Stringfield Dr. Susan Lewis Actor Eriq La Salle Dr. Peter Benton Actor Noah Wyle Dr. John Carter Actor Julianna Margulies Head Nurse Carol Hathaway Actor Gloria Reuben Jeanie Boulet Actor Red Buttons Jules 'Ruby' Rubadoux Guest Star Ron Rifkin Guest Star Mary Mara Loretta Sweet Guest Star Linda Lutz Mrs. Saunders Guest Star Ron Eldard Guest Star Carlos Gomez Paramedic Raul Melendez Guest Star Ellen Crawford Nurse Lydia Wright Guest Star Yvette Freeman Nurse Haleh Adams Guest Star Billye Ree Wallace Helen 'Silvie' Rubadoux Guest Star Michael Crichton Executive Producer John Wells Executive Producer