Goran Visnjic Dr. Luka Kovac Actor Maura Tierney Abby Lockhart Actor Mekhi Phifer Dr. Gregory Pratt Actor Parminder Nagra Dr. Neela Rasgotra Actor Linda Cardellini Nurse Samantha Taggart Actor Shane West Actor Scott Grimes Dr. Archie Morris Actor Laura Innes Dr. Kerry Weaver Actor John Stamos Dr. Tony Gates Actor Aasif Mandvi Manish Guest Star Sara Gilbert Jane Figler Guest Star Leland Orser Dr. Lucien Dubenko Guest Star Andy Dick Tommy Brewer Guest Star J.P. Manoux Dr. Dustin Crenshaw Guest Star Sean Young Anna Hayes Guest Star Deezer D Nurse Malik McGrath Guest Star Chloe Greenfield Sarah Riley Guest Star Sarah Avery Coach Jenny Guest Star Lyn Alicia Henderson Pamela Olbes Guest Star Christopher Chulack Executive Producer Michael Crichton Executive Producer David Zabel Executive Producer John Wells Executive Producer R. Scott Gemmill Executive Producer