Goran Visnjic Dr. Luka Kovac Actor Maura Tierney Abby Lockhart Actor Mekhi Phifer Dr. Gregory Pratt Actor Parminder Nagra Dr. Neela Rasgotra Actor Linda Cardellini Nurse Samantha Taggart Actor Scott Grimes Dr. Archie Morris Actor John Stamos Dr. Tony Gates Actor Aida Turturro Sheryl Hawkins Guest Star David Lyons Dr. Simon Brenner Guest Star Kari Matchett Dr. Skye Wexler Guest Star Leland Orser Dr. Lucien Dubenko Guest Star John Aylward Dr. Donald Anspaugh Guest Star Amy Aquino Dr. Janet Coburn Guest Star Aaron Yoo Kwan Li Guest Star Troy Evans Frank Martin Guest Star Yvette Freeman Nurse Haleh Adams Guest Star Amanda Foreman Missy Voltaire Guest Star Christopher Chulack Executive Producer Michael Crichton Executive Producer David Zabel Executive Producer John Wells Executive Producer R. Scott Gemmill Executive Producer