Seth MacFarlane Peter Griffin , Brian Griffin , Stewie Griffin , Tom Tucker , God , Steve Guttenberg , Mr. Berler , Christopher Columbus Voice, Executive Producer Alex Borstein Lois Griffin , Additional Voices Voice Seth Green Chris Griffin , Neil Goldman , Additional Voices Voice Mila Kunis Meg Griffin Voice Mike Henry Cleveland Brown Voice Lori Alan Diane Simmons Guest Voice Mike Barker Buff Guy Guest Voice Johnny Brennan Mort Goldman , Horace Guest Voice Michael Chiklis Cartoony Crewman , Mechanic Guest Voice Gary Cole Principal Shepard Guest Voice Ralph Garman Dustin Hoffman Guest Voice Mark Hentemann Chief McKenzie , Holden Caulfield Guest Voice D.D. Howard Jane Fonda Guest Voice Danny Smith Al Guest Voice Tara Strong Beth , Classmate , Teenage Girl Guest Voice Lisa Wilhoit Connie D'Amico Guest Voice Hugh Downs Himself Guest Voice Phil LaMarr Minister Guest Voice Nicole Sullivan Mrs. Goldman Guest Voice Abe Vigoda Himself Guest Voice Adam West Mayor Adam West Guest Voice Josh Peck Charlie Guest Voice David Zuckerman Executive Producer Pete Michels Director Peter Shin Director