Seth MacFarlane Peter Griffin , Stewie Griffin , Brian Griffin , Glenn Quagmire , Carter Pewterschmidt , God , Kool-Aid Guy Voice, Executive Producer Alex Borstein Lois Griffin , Asian Hooker Voice Seth Green Chris Griffin Voice Mila Kunis Meg Griffin Voice Mike Henry Cleveland Brown , John Herbert , Bruce the Performance Artist Voice Patrick Warburton Joe Swanson Voice Adam West Mayor Adam West Guest Voice Jennifer Tilly Bonnie Swanson Guest Voice Simon Cowell Himself Guest Voice Paula Abdul Herself Guest Voice Randy Jackson Himself Guest Voice Patrick Stewart Additional Voices Guest Voice David Boat Rupert Guest Voice Alexandra Breckenridge Cancer Sufferer Guest Voice Mark Hentemann Male Voices , Audience Member 1 Guest Voice Phil LaMarr Judge Guest Voice Danny Smith Second Caterpillar , Suitor , TV Announcer Guest Voice Alec Sulkin Baseball Announcer 1 , Voice Guest Voice John Viener Announcer , Announcer 2 , Baseball Announcer 2 , Fjurg Van Der Ploeg , Henry Kissinger , Mark Wahlberg , Matthew Fox Guest Voice David Zuckerman Executive Producer John Holmquist Director James Purdum Director Peter Shin Director