Seth MacFarlane Peter Griffin , Brian Griffin , Stewie Griffin , Glenn Quagmire , Tom Tucker , Dr. Elmer Hartman , Barack Obama Voice, Executive Producer Alex Borstein Lois Griffin Voice Seth Green Chris Griffin Voice Mila Kunis Meg Griffin Voice Mike Henry Various Voice Patrick Warburton Joe Swanson Voice Johnny Brennan Horace Guest Voice Yvette Nicole Brown Black Sassy Nurse Guest Voice Drew Carey Himself Guest Voice Gary Cole Principal Shepherd Guest Voice John Viener Flower Guest Voice Christine Lakin Joyce Kinney Guest Voice Megan Grano Additional Voices Guest Voice Ralph Garman Additional Voices Guest Voice Rachael MacFarlane Additional Voices Guest Voice Danny Smith Additional Voices Guest Voice Scott Baio Charles (archive footage) Guest Voice Willie Aames Buddy Lembeck (archive footage) Guest Voice Josie Davis Sarah Powell (archive footage) Guest Voice Nicole Eggert Jamie Powell (archive footage) Guest Voice Sandra Kerns Ellen Powell (archive footage) Guest Voice David Zuckerman Executive Producer Pete Michels Director James Purdum Director Peter Shin Director