Peter Casey Creator, Executive Producer David Angell Creator, Executive Producer David Lee Creator, Executive Producer, Director Kelsey Grammer Dr. Frasier Crane Actor, Executive Producer John Mahoney Martin Crane Actor Jane Leeves Daphne Moon Actor David Hyde Pierce Dr. Niles Crane Actor Peri Gilpin Roz Doyle Actor Dan Butler Bob "Bulldog" Briscoe Guest Star Marsha Mason Sherry Dempsey Guest Star Lindsay Frost Samantha Pierce Guest Star Cynthia Lamontagne Annie Guest Star Stephanie Faracy Mimi Guest Star Albert Macklin Masseur Guest Star Edward Hibbert Gil Chesterton Guest Star Mark Blum John Guest Star Amy Landers Waitress Guest Star Halle Berry Betsy Guest Voice Heather Lee Toffee McIntosh Guest Star Demene Hall Conductor Guest Star Yasemin Baytok Cindy Guest Star Norman B. Rice Himself - Mayor of Seattle Guest Star James Harper Karl Guest Star Sheldon Epps Director Suzanne Martin Writer David Lloyd Writer Rob Hanning Writer Jay Kogen Writer Christopher Lloyd Writer, Executive Producer Joe Keenan Writer Jeff Melman Director Pamela Fryman Director Rob Greenberg Writer Jeffrey Richman Writer