David Angell Creator, Executive Producer Peter Casey Creator, Executive Producer David Lee Creator, Executive Producer Kelsey Grammer Dr. Frasier Crane Actor, Executive Producer John Mahoney Martin Crane Actor Jane Leeves Daphne Moon Actor David Hyde Pierce Dr. Niles Crane Actor Peri Gilpin Roz Doyle Actor Bob Dishy Dr. Schenkman Guest Star Amy Van Nostrand Janice Guest Star John Waters Roger Guest Voice Rob Reiner Bill Guest Voice Bess Myerson Mary Guest Voice Christopher Lloyd Executive Producer Jeff Melman Director David Lloyd Writer