Kelsey Grammer Dr. Frasier Crane Actor John Mahoney Martin Crane Actor Jane Leeves Daphne Moon Actor David Hyde Pierce Dr. Niles Crane Actor Peri Gilpin Roz Doyle Actor Eva Marie Saint Joanna Doyle Guest Star Alice Playten Bonnie Guest Star Rocky McMurray Shangri-lino Guest Star Phil Donahue Larry Guest Voice Marlo Thomas Sophie Guest Voice David Angell Executive Producer Peter Casey Executive Producer David Lee Executive Producer Christopher Lloyd Executive Producer Pamela Fryman Director Janis Hirsch Writer