Kelsey Grammer Dr. Frasier Crane Actor, Executive Producer John Mahoney Martin Crane Actor Jane Leeves Daphne Moon Actor David Hyde Pierce Dr. Niles Crane Actor Peri Gilpin Roz Doyle Actor Tony Goldwyn Roger Guest Star Patrick Kerr Noel Shempsky Guest Star Ashley Lauren Thomas Alice May Doyle Guest Star Stephon Fuller Jason Guest Star Jill Talley Cheryl Guest Star Bernard Zilinskas Dennis Guest Star Tom McGowan Kenny Daly Guest Star David Angell Executive Producer Peter Casey Executive Producer David Lee Executive Producer Mark Reisman Executive Producer Dan O'Shannon Executive Producer Katy Garretson Director Saladin K. Patterson Writer