Kelsey Grammer Dr. Frasier Crane Actor, Executive Producer John Mahoney Martin Crane Actor Jane Leeves Daphne Moon Actor David Hyde Pierce Dr. Niles Crane Actor Peri Gilpin Roz Doyle Actor Wendie Malick Ronee Lawrence Guest Star Julia Sweeney Ann Hodges Guest Star Krista Allen Liz Wright Guest Star Lauri Johnson Mrs. Gablyczyck Guest Star Anthony Crivello Maitre D' Guest Star Craig Zimmerman Waiter Guest Star Paul Michael Restaurant Owner Guest Star Tom McGowan Kenny Daly Guest Star David Angell Executive Producer Peter Casey Executive Producer David Lee Executive Producer Mark Reisman Executive Producer Dan O'Shannon Executive Producer Sheldon Epps Director Lori Kirkland Baker Writer