Ellen Pompeo Dr. Meredith Grey Actor Patrick Dempsey Dr. Derek Shepherd Actor James Pickens Jr. Dr. Richard Webber Actor T.R. Knight Dr. George O'Malley Actor Sandra Oh Dr. Cristina Yang Actor Katherine Heigl Dr. Izzie Stevens Actor Chandra Wilson Dr. Miranda Bailey Actor Isaiah Washington Dr. Preston Burke Actor Justin Chambers Dr. Alex Karev Actor Kate Walsh Dr. Addison Montgomery Actor Sara Ramirez Guest Star Jeffrey Dean Morgan Guest Star Ann Cusack Guest Star Jonathan Slavin Guest Star Mark Harelik Guest Star Matt Roth Guest Star Cress Williams Guest Star Sarah Utterback Guest Star Noah Gray-Cabey Guest Star Cathy Lind Hayes Guest Star Jeremy Rabb Guest Star Ray Ford Guest Star Shonda Rhimes Executive Producer Mark Gordon Executive Producer Betsy Beers Executive Producer James D. Parriott Executive Producer Stacy McKee Writer Wendey Stanzler Director