Ellen Pompeo Dr. Meredith Grey Actor Patrick Dempsey Dr. Derek Shepherd Actor Sandra Oh Dr. Cristina Yang Actor Katherine Heigl Dr. Izzie Stevens Actor Justin Chambers Dr. Alex Karev Actor T.R. Knight Dr. George O'Malley Actor Chandra Wilson Dr. Miranda Bailey Actor James Pickens Jr. Dr. Richard Webber Actor Sara Ramirez Dr. Callie Torres Actor Eric Dane Dr. Mark Sloan Actor Chyler Leigh Dr. Lexie Grey Actor Brooke Smith Dr. Erica Hahn Actor Jeff Perry Guest Star Rockmond Dunbar Guest Star Stephanie March Guest Star Vicki Lewis Guest Star David Burke Guest Star Kurt Fuller Guest Star Enuka Okuma Guest Star Braeden Lemasters Guest Star Mark Saul Guest Star Amrapali Ambegaokar Guest Star Linda Eve Miller Guest Star Shonda Rhimes Executive Producer Mark Gordon Executive Producer Betsy Beers Executive Producer James D. Parriott Executive Producer Tony Phelan Writer Joan Rater Writer Jeff Melman Director