Hugh Laurie Dr. Gregory House Actor Lisa Edelstein Dr. Lisa Cuddy Actor Robert Sean Leonard Dr. James Wilson Actor Jennifer Morrison Dr. Allison Cameron Actor Omar Epps Dr. Eric Foreman Actor Jesse Spencer Dr. Robert Chase Actor Roxanne Hart Margo Davis Guest Star John Patrick Amedori Matt Davis Guest Star Shirley Knight Georgia Adams Guest Star Kurt Fuller Mark Adams Guest Star McNally Sagal Mrs. Miller Guest Star Molly Mankiewicz Amy - Blonde Woman Guest Star Christopher Malpede Math Whiz Guest Star Kenya D. Williamson Nurse Guest Star Ulysses Lee Chi Ling Guest Star Jim Lau Chou-Young Ling Guest Star Linda Wang Jen Ling Guest Star Andy Milder Bus Driver Guest Star Paul Attanasio Executive Producer Katie Jacobs Executive Producer David Shore Executive Producer Bryan Singer Executive Producer Guy Ferland Director Matt Witten Writer